Clinical outcomes after injection of a compounded pharmaceutical for prophylaxis after cataract  surgery: a large-scale review

Curr Opin Ophthalmol 2017, 28:58–62

백내장 수술후 안약을 안쓰는 방법에 대한연구입니다.

수술중 인공수정체를 넣고나서

약을 칵테일처럼 만들어 눈속에 넣는 방법으로

효과가 좋고 부작용이 적었다고 하네요…

아직까지는 연구가 더 필요하겠지만,, 수술 후 안약을 안넣을수 있다니 획기적이네요

연구하는 병원!! 앞서가는 대전 민들레안과에서…

A transzonular injection of 0.2 ml TMV (3.0mg triamcinolone acetonide, 0.2mg moxifloxacin, and 2.0mg vancomycin) was administered into the anterior vitreous after IOL implantation but before viscoelastic removal. Viscoelastic was used to expand the ciliary sulcus prior to injection. The TMV formulation was slowly injected through the zonules via the ciliary sulcus inferonasally with a 30- ga Rycroft cannula. Intravitreal TMV placement was visually confirmed by the appearance of a white plume in the vitreous (Fig. 1). A second or third TMV injection was permitted if the surgeon deemed the first (or second) injection to be inadequate. Viscoelastic was removed immediately after administration and confirmation of the TMV injection.

  • There is a need for simple prophylactic therapies that safely and effectively reduce the risk of postoperative endophthalmitis, inflammation, and CME associated
    with cataract surgery.

  • Eye drops are the current standard of care, but these regimens are not always simple and often create a burden for the patient that can decrease adherence and influence overall surgical outcomes.

  • Single-use intraocular injections, including a regulated, compounded formulation of triamcinolone– moxifloxacin–vancomycin, have been developed as a simple prophylactic alternative.

  • A retrospective chart review of 1541 cataract surgeries from a single-specialty surgical practice showed that a prophylactic transzonular intravitreal injection of
    triamcinolone–moxifloxacin–vancomycin eliminated the need for supplemental postoperative medication in 92% of cases

  • Triamcinolone–moxifloxacin–vancomycin is an advanced-technology prophylactic that can potentially change the postoperative cataract care paradigm, and
    this is the first clinical report on real-world triamcinolone–moxifloxacin–vancomycin safety and effectiveness.

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